Osteoinductive silk–silica composite biomaterials for bone regeneration

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منابع مشابه

Biomaterials for bone regeneration.

OBJECTIVE This article reviews the literature on biomaterials used for bone regeneration. MATERIAL AND METHOD A total of seventeen bibliographic sources were found using the MEDLINE database and to avoid the variability of the search terms the thesaurus Mesh was used. RESULTS These materials act essentially due to their osteoconductive ability, although their osteoinductive capacity is bein...

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Bone-grafting techniques either with autografts or allografts still represent a challenge for reconstructive surgery.Allografts and autografts are the current strategies for filling bone defects and subsequent repair but each have drawbacks. Synthetic bone-graft substitutes, developed in an effort to overcome the inherent limitations of autograft and allograft, represent an alternative strategy...

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Functionalized Silk Biomaterials for Bone Regeneration

Sílvia Gomes 2, , Isabel B. Leonor , João F. Mano , Rui L. Reis , David L. Kaplan 3B’s Research Group Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, 4806-909 Taipas, Guimarães, Portugal 2 IBB Institute for Biotechnology and Bioengineering, PT Associated Laboratory, ...

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Composite Hydrogels for Bone Regeneration

Over the past few decades, bone related disorders have constantly increased. Among all pathological conditions, osteoporosis is one of the most common and often leads to bone fractures. This is a massive burden and it affects an estimated 3 million people only in the UK. Furthermore, as the population ages, numbers are due to increase. In this context, novel biomaterials for bone fracture regen...

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Siliceous mesostructured cellular foams/poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) composite biomaterials for bone regeneration

Osteoinductive and biodegradable composite biomaterials for bone regeneration were prepared by combining poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) with siliceous mesostructured cellular foams (SMC), using the porogen leaching method. Surface hydrophilicity, morphology, and recombinant human bone morphogenetic protein 2 adsorption/release behavior of the SMC/PHBHHx scaffolds were an...

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ژورنال

عنوان ژورنال: Biomaterials

سال: 2010

ISSN: 0142-9612

DOI: 10.1016/j.biomaterials.2010.07.109